FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective c...

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Detalles Bibliográficos
Autores principales: Pozniak, Marta, Sokolowska‐Wedzina, Aleksandra, Jastrzebski, Kamil, Szymczyk, Jakub, Porebska, Natalia, Krzyscik, Mateusz Adam, Zakrzewska, Malgorzata, Miaczynska, Marta, Otlewski, Jacek, Opalinski, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463352/
https://www.ncbi.nlm.nih.gov/pubmed/32511887
http://dx.doi.org/10.1002/1878-0261.12740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463352/
https://www.ncbi.nlm.nih.gov/pubmed/32511887
http://dx.doi.org/10.1002/1878-0261.12740

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