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Quercetin Downregulates Cyclooxygenase-2 Expression and HIF-1α/VEGF Signaling-Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm

OBJECTIVE: Abdominal aortic aneurysm (AAA) development has been characterized by increased expression of vascular endothelial growth factor (VEGF), which contributes to angiogenesis via cyclooxygenase-2 (COX-2). Quercetin, one of the most common and well-researched flavonoids and abundant in vegetab...

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Detalles Bibliográficos
Autores principales: Wang, Lian, Wu, Haiwei, Xiong, Lei, Liu, Xiaolong, Yang, Nan, Luo, Liguo, Qin, Tao, Zhu, Xian, Shen, Zhonghua, Jing, Hua, Chen, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463408/
https://www.ncbi.nlm.nih.gov/pubmed/32908926
http://dx.doi.org/10.1155/2020/9485398