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Quercetin Downregulates Cyclooxygenase-2 Expression and HIF-1α/VEGF Signaling-Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm
OBJECTIVE: Abdominal aortic aneurysm (AAA) development has been characterized by increased expression of vascular endothelial growth factor (VEGF), which contributes to angiogenesis via cyclooxygenase-2 (COX-2). Quercetin, one of the most common and well-researched flavonoids and abundant in vegetab...
Autores principales: | Wang, Lian, Wu, Haiwei, Xiong, Lei, Liu, Xiaolong, Yang, Nan, Luo, Liguo, Qin, Tao, Zhu, Xian, Shen, Zhonghua, Jing, Hua, Chen, Jinming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463408/ https://www.ncbi.nlm.nih.gov/pubmed/32908926 http://dx.doi.org/10.1155/2020/9485398 |
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