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Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells

Paclitaxel is a microtubule stabilizing agent and a successful drug for cancer chemotherapy inducing, however, adverse effects. To reduce the effective dose of paclitaxel, we searched for pharmaceutics which could potentiate its therapeutic effect. We screened a chemical library and selected Carba1,...

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Detalles Bibliográficos
Autores principales: Peronne, Lauralie, Denarier, Eric, Rai, Ankit, Prudent, Renaud, Vernet, Audrey, Suzanne, Peggy, Ramirez-Rios, Sacnicté, Michallet, Sophie, Guidetti, Mélanie, Vollaire, Julien, Lucena-Agell, Daniel, Ribba, Anne-Sophie, Josserand, Véronique, Coll, Jean-Luc, Dallemagne, Patrick, Díaz, J. Fernando, Oliva, María Ángela, Sadoul, Karin, Akhmanova, Anna, Andrieux, Annie, Lafanechère, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463452/
https://www.ncbi.nlm.nih.gov/pubmed/32781579
http://dx.doi.org/10.3390/cancers12082196