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The Application of Inosine 5′-Monophosphate Dehydrogenase Activity Determination in Peripheral Blood Mononuclear Cells for Monitoring Mycophenolate Mofetil Therapy in Children with Nephrotic Syndrome

In pediatric nephrotic syndrome, recommended mycophenolic acid (MPA) pharmacokinetics are higher than those for transplant recipients. In MPA therapeutic monitoring, inosine-5′-monophosphate dehydrogenase (IMPDH) activity may be useful. We modified the method established for renal transplant recipie...

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Detalles Bibliográficos
Autores principales: Sobiak, Joanna, Jóźwiak, Alicja, Wziętek, Honorata, Zachwieja, Jacek, Ostalska-Nowicka, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463457/
https://www.ncbi.nlm.nih.gov/pubmed/32824803
http://dx.doi.org/10.3390/ph13080200