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The Application of Inosine 5′-Monophosphate Dehydrogenase Activity Determination in Peripheral Blood Mononuclear Cells for Monitoring Mycophenolate Mofetil Therapy in Children with Nephrotic Syndrome
In pediatric nephrotic syndrome, recommended mycophenolic acid (MPA) pharmacokinetics are higher than those for transplant recipients. In MPA therapeutic monitoring, inosine-5′-monophosphate dehydrogenase (IMPDH) activity may be useful. We modified the method established for renal transplant recipie...
Autores principales: | Sobiak, Joanna, Jóźwiak, Alicja, Wziętek, Honorata, Zachwieja, Jacek, Ostalska-Nowicka, Danuta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463457/ https://www.ncbi.nlm.nih.gov/pubmed/32824803 http://dx.doi.org/10.3390/ph13080200 |
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