Structure and Antiparasitic Activity Relationship of Alkylphosphocholine Analogues against Leishmania donovani

Miltefosine (Milt) is the only oral treatment for visceral leishmaniasis (VL) but its use is associated with adverse effects, e.g., teratogenicity, vomiting, diarrhoea. Understanding how its chemical structure induces cytotoxicity, whilst not compromising its anti-parasitic efficacy, could identify...

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Detalles Bibliográficos
Autores principales: Ahmed, Humera, Carter, Katharine C., Williams, Roderick A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463460/
https://www.ncbi.nlm.nih.gov/pubmed/32722326
http://dx.doi.org/10.3390/microorganisms8081117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463460/
https://www.ncbi.nlm.nih.gov/pubmed/32722326
http://dx.doi.org/10.3390/microorganisms8081117

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