Automated GMP-Compliant Production of [(68)Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans

Introduction: [(68)Ga]Ga-DO3A-VS-Cys(40)-Tuna-2 (previously published as [(68)Ga]Ga-DO3A-VS-Cys(40)-S01-GCG) has shown high-affinity specific binding to the glucagon receptor (GCGR) in vitro and in vivo in rats and non-human primates in our previous studies, confirming the suitability of the tracer...

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Detalles Bibliográficos
Autores principales: Wagner, Michael, Doverfjord, Johan G., Tillner, Joachim, Antoni, Gunnar, Haack, Torsten, Bossart, Martin, Laitinen, Iina, Johansson, Lars, Pierrou, Stefan, Eriksson, Olof, Velikyan, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463542/
https://www.ncbi.nlm.nih.gov/pubmed/32752075
http://dx.doi.org/10.3390/ph13080176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463542/
https://www.ncbi.nlm.nih.gov/pubmed/32752075
http://dx.doi.org/10.3390/ph13080176

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