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iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation

The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack of efficient regenerative response for remyelination, which is carried out by the endogenous population of adult oligoprogenitor cells (OPCs) after proper activation. OPCs must proliferate and migrate to the l...

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Detalles Bibliográficos
Autores principales: Lopez-Caraballo, Lidia, Martorell-Marugan, Jordi, Carmona-Sáez, Pedro, Gonzalez-Munoz, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463559/
https://www.ncbi.nlm.nih.gov/pubmed/32751289
http://dx.doi.org/10.3390/cells9081803