Cargando…

TIF1 Proteins in Genome Stability and Cancer

Genomic instability is a hallmark of cancer cells which results in excessive DNA damage. To counteract this, cells have evolved a tightly regulated DNA damage response (DDR) to rapidly sense DNA damage and promote its repair whilst halting cell cycle progression. The DDR functions predominantly with...

Descripción completa

Detalles Bibliográficos
Autores principales: McAvera, Roisin M., Crawford, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463590/
https://www.ncbi.nlm.nih.gov/pubmed/32731534
http://dx.doi.org/10.3390/cancers12082094