Ex Vivo Models Simulating the Bone Marrow Environment and Predicting Response to Therapy in Multiple Myeloma

Multiple myeloma (MM) remains incurable despite the abundance of novel drugs. As it has been previously shown, preclinical 2D models fail to predict disease progression due to their inability to simulate the microenvironment of the bone marrow. In this review, we focus on 3D models and present all c...

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Detalles Bibliográficos
Autores principales: Papadimitriou, Konstantinos, Kostopoulos, Ioannis V., Tsopanidou, Anastasia, Orologas-Stavrou, Nikolaos, Kastritis, Efstathios, Tsitsilonis, Ourania E., Dimopoulos, Meletios A., Terpos, Evangelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463609/
https://www.ncbi.nlm.nih.gov/pubmed/32707884
http://dx.doi.org/10.3390/cancers12082006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463609/
https://www.ncbi.nlm.nih.gov/pubmed/32707884
http://dx.doi.org/10.3390/cancers12082006

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