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Ex Vivo Models Simulating the Bone Marrow Environment and Predicting Response to Therapy in Multiple Myeloma
Multiple myeloma (MM) remains incurable despite the abundance of novel drugs. As it has been previously shown, preclinical 2D models fail to predict disease progression due to their inability to simulate the microenvironment of the bone marrow. In this review, we focus on 3D models and present all c...
Autores principales: | Papadimitriou, Konstantinos, Kostopoulos, Ioannis V., Tsopanidou, Anastasia, Orologas-Stavrou, Nikolaos, Kastritis, Efstathios, Tsitsilonis, Ourania E., Dimopoulos, Meletios A., Terpos, Evangelos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463609/ https://www.ncbi.nlm.nih.gov/pubmed/32707884 http://dx.doi.org/10.3390/cancers12082006 |
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