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Cancer Stem Cells, Quo Vadis? The Notch Signaling Pathway in Tumor Initiation and Progression

The Notch signaling pathway regulates cell proliferation, cytodifferentiation and cell fate decisions in both embryonic and adult life. Several aspects of stem cell maintenance are dependent from the functionality and fine tuning of the Notch pathway. In cancer, Notch is specifically involved in pre...

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Detalles Bibliográficos
Autores principales: Meisel, Christian T., Porcheri, Cristina, Mitsiadis, Thimios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463613/
https://www.ncbi.nlm.nih.gov/pubmed/32796631
http://dx.doi.org/10.3390/cells9081879