Protein–Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations

Because proteins are fundamental to most biological processes, many genetic diseases can be traced back to single nucleotide variants (SNVs) that cause changes in protein sequences. However, not all SNVs that result in amino acid substitutions cause disease as each residue is under different structu...

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Detalles Bibliográficos
Autores principales: Wong, Eric T. C., So, Victor, Guron, Mike, Kuechler, Erich R., Malhis, Nawar, Bui, Jennifer M., Gsponer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463635/
https://www.ncbi.nlm.nih.gov/pubmed/32722039
http://dx.doi.org/10.3390/biom10081097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463635/
https://www.ncbi.nlm.nih.gov/pubmed/32722039
http://dx.doi.org/10.3390/biom10081097

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