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Organotypic Co-Cultures as a Novel 3D Model for Head and Neck Squamous Cell Carcinoma

Background: Head and neck squamous cell carcinomas (HNSCC) are phenotypically and molecularly heterogeneous and frequently develop therapy resistance. Reliable patient-derived 3D tumor models are urgently needed to further study the complex pathogenesis of these tumors and to overcome treatment fail...

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Detalles Bibliográficos
Autores principales: Engelmann, Luca, Thierauf, Julia, Koerich Laureano, Natalia, Stark, Hans-Juergen, Prigge, Elena-Sophie, Horn, Dominik, Freier, Kolja, Grabe, Niels, Rong, Chao, Federspil, Philippe, Zaoui, Karim, Plinkert, Peter K., Rotter, Nicole, von Knebel Doeberitz, Magnus, Hess, Jochen, Affolter, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463661/
https://www.ncbi.nlm.nih.gov/pubmed/32824777
http://dx.doi.org/10.3390/cancers12082330