Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

Repetitive intermittent hyperglycemia (RIH) is an independent risk factor for complications associated with type-2 diabetes (T2D). Glucose fluctuations commonly occur in T2D patients with poor glycemic control or following intensive therapy. Reducing blood glucose as well as glucose fluctuations is...

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Detalles Bibliográficos
Autores principales: Al-Rashed, Fatema, Sindhu, Sardar, Arefanian, Hossein, Al Madhoun, Ashraf, Kochumon, Shihab, Thomas, Reeby, Al-Kandari, Sarah, Alghaith, Abdulwahab, Jacob, Texy, Al-Mulla, Fahd, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463685/
https://www.ncbi.nlm.nih.gov/pubmed/32806763
http://dx.doi.org/10.3390/cells9081892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463685/
https://www.ncbi.nlm.nih.gov/pubmed/32806763
http://dx.doi.org/10.3390/cells9081892

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