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Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity

Gold nanoparticles (AuNPs) are considered nontoxic upon acute exposure, at least when they are equal or above 5 nm size. However, the safeguard mechanisms contributing to maintain cell viability are scarcely explored so far. Here, we investigated the cyto-protective role of Glyoxalase 1 (Glo1), a ke...

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Detalles Bibliográficos
Autores principales: Gambelunghe, Angela, Giovagnoli, Stefano, Di Michele, Alessandro, Boncompagni, Simona, Dell’Omo, Marco, Leopold, Kerstin, Iavicoli, Ivo, Talesa, Vincenzo Nicola, Antognelli, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463694/
https://www.ncbi.nlm.nih.gov/pubmed/32756399
http://dx.doi.org/10.3390/antiox9080697