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Cancer Cell Acid Adaptation Gene Expression Response Is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

The acidic pH of the tumor microenvironment plays a critical role in driving cancer development toward a more aggressive phenotype, but the underlying mechanisms are unclear. To this end, phenotypic and genotypic changes induced by adaptation of cancer cells to chronic acidosis have been studied. Ho...

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Detalles Bibliográficos
Autores principales: Yao, Jiayi, Czaplinska, Dominika, Ialchina, Renata, Schnipper, Julie, Liu, Bin, Sandelin, Albin, Pedersen, Stine Falsig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463722/
https://www.ncbi.nlm.nih.gov/pubmed/32764426
http://dx.doi.org/10.3390/cancers12082183