Multifaceted Roles of DNA Methylation in Neoplastic Transformation, from Tumor Suppressors to EMT and Metastasis

Among the major mechanisms involved in tumorigenesis, DNA methylation is an important epigenetic modification impacting both genomic stability and gene expression. Methylation of promoter-proximal CpG islands (CGIs) and transcriptional silencing of tumor suppressors represent the best characterized...

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Detalles Bibliográficos
Autores principales: Casalino, Laura, Verde, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463745/
https://www.ncbi.nlm.nih.gov/pubmed/32806509
http://dx.doi.org/10.3390/genes11080922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463745/
https://www.ncbi.nlm.nih.gov/pubmed/32806509
http://dx.doi.org/10.3390/genes11080922

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