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C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities

Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules. They are difficult to synthesize chemically, but enzymatic synthesis production is a desirable pathway. Cyclic dipeptide prenyltransfera...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Zhang, Hongchi, Wu, Weiqiang, Li, Hui, An, Zhipeng, Zhou, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463755/
https://www.ncbi.nlm.nih.gov/pubmed/32806659
http://dx.doi.org/10.3390/molecules25163676