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Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential

Sweet cherries (Prunus avium L.) are highly appreciated fruits for their taste, color, nutritional value, and beneficial health effects. In this work, seven new cultivars of sweet cherry were investigated for their main quality traits and nutraceutical value. The phytochemical profile of three class...

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Autores principales: Antognoni, Fabiana, Potente, Giulia, Mandrioli, Roberto, Angeloni, Cristina, Freschi, Michela, Malaguti, Marco, Hrelia, Silvana, Lugli, Stefano, Gennari, Fabio, Muzzi, Enrico, Tartarini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463759/
https://www.ncbi.nlm.nih.gov/pubmed/32731644
http://dx.doi.org/10.3390/antiox9080677
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author Antognoni, Fabiana
Potente, Giulia
Mandrioli, Roberto
Angeloni, Cristina
Freschi, Michela
Malaguti, Marco
Hrelia, Silvana
Lugli, Stefano
Gennari, Fabio
Muzzi, Enrico
Tartarini, Stefano
author_facet Antognoni, Fabiana
Potente, Giulia
Mandrioli, Roberto
Angeloni, Cristina
Freschi, Michela
Malaguti, Marco
Hrelia, Silvana
Lugli, Stefano
Gennari, Fabio
Muzzi, Enrico
Tartarini, Stefano
author_sort Antognoni, Fabiana
collection PubMed
description Sweet cherries (Prunus avium L.) are highly appreciated fruits for their taste, color, nutritional value, and beneficial health effects. In this work, seven new cultivars of sweet cherry were investigated for their main quality traits and nutraceutical value. The phytochemical profile of three classes of phenolic compounds and the antioxidant activity of the new cultivars were investigated through high-performance liquid chromatography with diode array detection (HPLC-DAD) and spectrophotometric assays, respectively, and compared with those of commonly commercialized cultivars. Cyanidine-3-O-rutinoside was the main anthocyanin in all genotypes, and its levels in some new cultivars were about three-fold higher than in commercial ones. The ORAC-assayed antioxidant capacity was positively correlated with the total anthocyanin index. The nutraceutical value of the new cultivars was investigated in terms of antioxidant/neuroprotective capacity in neuron-like SH-SY5Y cells. Results demonstrated that the new cultivars were more effective in counteracting oxidative stress and were also able to upregulate brain-derived neurotrophic factor (BDNF), a pro-survival neurotrophin, suggesting their potential pleiotropic role in counteracting neurodegenerations.
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spelling pubmed-74637592020-09-02 Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential Antognoni, Fabiana Potente, Giulia Mandrioli, Roberto Angeloni, Cristina Freschi, Michela Malaguti, Marco Hrelia, Silvana Lugli, Stefano Gennari, Fabio Muzzi, Enrico Tartarini, Stefano Antioxidants (Basel) Article Sweet cherries (Prunus avium L.) are highly appreciated fruits for their taste, color, nutritional value, and beneficial health effects. In this work, seven new cultivars of sweet cherry were investigated for their main quality traits and nutraceutical value. The phytochemical profile of three classes of phenolic compounds and the antioxidant activity of the new cultivars were investigated through high-performance liquid chromatography with diode array detection (HPLC-DAD) and spectrophotometric assays, respectively, and compared with those of commonly commercialized cultivars. Cyanidine-3-O-rutinoside was the main anthocyanin in all genotypes, and its levels in some new cultivars were about three-fold higher than in commercial ones. The ORAC-assayed antioxidant capacity was positively correlated with the total anthocyanin index. The nutraceutical value of the new cultivars was investigated in terms of antioxidant/neuroprotective capacity in neuron-like SH-SY5Y cells. Results demonstrated that the new cultivars were more effective in counteracting oxidative stress and were also able to upregulate brain-derived neurotrophic factor (BDNF), a pro-survival neurotrophin, suggesting their potential pleiotropic role in counteracting neurodegenerations. MDPI 2020-07-28 /pmc/articles/PMC7463759/ /pubmed/32731644 http://dx.doi.org/10.3390/antiox9080677 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Antognoni, Fabiana
Potente, Giulia
Mandrioli, Roberto
Angeloni, Cristina
Freschi, Michela
Malaguti, Marco
Hrelia, Silvana
Lugli, Stefano
Gennari, Fabio
Muzzi, Enrico
Tartarini, Stefano
Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title_full Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title_fullStr Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title_full_unstemmed Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title_short Fruit Quality Characterization of New Sweet Cherry Cultivars as a Good Source of Bioactive Phenolic Compounds with Antioxidant and Neuroprotective Potential
title_sort fruit quality characterization of new sweet cherry cultivars as a good source of bioactive phenolic compounds with antioxidant and neuroprotective potential
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463759/
https://www.ncbi.nlm.nih.gov/pubmed/32731644
http://dx.doi.org/10.3390/antiox9080677
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