Differences in Viral RNA Synthesis but Not Budding or Entry Contribute to the In Vitro Attenuation of Reston Virus Compared to Ebola Virus

Most filoviruses cause severe disease in humans. For example, Ebola virus (EBOV) is responsible for the two most extensive outbreaks of filovirus disease to date, with case fatality rates of 66% and 40%, respectively. In contrast, Reston virus (RESTV) is apparently apathogenic in humans, and while t...

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Detalles Bibliográficos
Autores principales: Bodmer, Bianca S., Greßler, Josephin, Schmidt, Marie L., Holzerland, Julia, Brandt, Janine, Braun, Stefanie, Groseth, Allison, Hoenen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463789/
https://www.ncbi.nlm.nih.gov/pubmed/32796523
http://dx.doi.org/10.3390/microorganisms8081215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463789/
https://www.ncbi.nlm.nih.gov/pubmed/32796523
http://dx.doi.org/10.3390/microorganisms8081215

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