Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles

An efficient construction of imidazole ring by a Cs(2)CO(3)-promoted annulation of amidoximes with terminal alkynes in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted imidazoles in good yields under transition...

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Detalles Bibliográficos
Autores principales: Mehmood, Hina, Iqbal, Muhammad Asif, Lu, Le, Hua, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463794/
https://www.ncbi.nlm.nih.gov/pubmed/32784900
http://dx.doi.org/10.3390/molecules25163621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463794/
https://www.ncbi.nlm.nih.gov/pubmed/32784900
http://dx.doi.org/10.3390/molecules25163621

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