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In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B

Amphotericin B (AmpB), one of the most commonly used agents in the treatment of severe fungal infections and life-threatening parasitic diseases such as visceral Leishmaniasis, has a negligible oral bioavailability, primarily due to a low solubility and permeability. To develop an oral formulation,...

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Detalles Bibliográficos
Autores principales: Kontogiannidou, Eleni, Meikopoulos, Thomas, Gika, Helen, Panteris, Emmanuel, Vizirianakis, Ioannis S., Müllertz, Anette, Fatouros, Dimitrios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463809/
https://www.ncbi.nlm.nih.gov/pubmed/32722400
http://dx.doi.org/10.3390/pharmaceutics12080699