Trabectedin and Lurbinectedin Extend Survival of Mice Bearing C26 Colon Adenocarcinoma, without Affecting Tumor Growth or Cachexia

Trabectedin (ET743) and lurbinectedin (PM01183) limit the production of inflammatory cytokines that are elevated during cancer cachexia. Mice carrying C26 colon adenocarcinoma display cachexia (i.e., premature death and body wasting with muscle, fat and cardiac tissue depletion), high levels of infl...

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Detalles Bibliográficos
Autores principales: Aquila, Giorgio, Re Cecconi, Andrea David, Forti, Mara, Frapolli, Roberta, Bello, Ezia, Novelli, Deborah, Russo, Ilaria, Licandro, Simonetta Andrea, Staszewsky, Lidia, Martinelli, Giulia Benedetta, Talamini, Laura, Pasetto, Laura, Resovi, Andrea, Giavazzi, Raffaella, Scanziani, Eugenio, Careccia, Giorgia, Vénéreau, Emilie, Masson, Serge, Latini, Roberto, D’Incalci, Maurizio, Piccirillo, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463843/
https://www.ncbi.nlm.nih.gov/pubmed/32824440
http://dx.doi.org/10.3390/cancers12082312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463843/
https://www.ncbi.nlm.nih.gov/pubmed/32824440
http://dx.doi.org/10.3390/cancers12082312

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