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Does Siponimod Exert Direct Effects in the Central Nervous System?
The modulation of the sphingosine 1-phosphate receptor is an approved treatment for relapsing multiple sclerosis because of its anti-inflammatory effect of retaining lymphocytes in lymph nodes. Different sphingosine 1-phosphate receptor subtypes are expressed in the brain and spinal cord, and their...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463861/ https://www.ncbi.nlm.nih.gov/pubmed/32722245 http://dx.doi.org/10.3390/cells9081771 |