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Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H(2)S/Ca(v)3.2 Signaling in Mice
Cystitis-related bladder pain involves RAGE activation by HMGB1, and increased Ca(v)3.2 T-type Ca(2+) channel activity by H(2)S, generated by upregulated cystathionine-γ-lyase (CSE) in mice treated with cyclophosphamide (CPA). We, thus, investigated possible crosstalk between the HMGB1/RAGE and CSE/...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463894/ https://www.ncbi.nlm.nih.gov/pubmed/32707767 http://dx.doi.org/10.3390/cells9081748 |