The Impact of Coilin Nonsynonymous SNP Variants E121K and V145I on Cell Growth and Cajal Body Formation: The First Characterization

Coilin is the main component of Cajal body (CB), a membraneless organelle that is involved in the biogenesis of ribonucleoproteins and telomerase, cell cycle, and cell growth. The disruption of CBs is linked to neurodegenerative diseases and potentially cancers. The coilin gene (COIL) contains two n...

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Detalles Bibliográficos
Autores principales: Yao, Yue, Tan, Heng Wee, Liang, Zhan-Ling, Wu, Gao-Qi, Xu, Yan-Ming, Lau, Andy T. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463897/
https://www.ncbi.nlm.nih.gov/pubmed/32764415
http://dx.doi.org/10.3390/genes11080895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463897/
https://www.ncbi.nlm.nih.gov/pubmed/32764415
http://dx.doi.org/10.3390/genes11080895

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