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Interplay between Cellular Metabolism and the DNA Damage Response in Cancer

Metabolism is a fundamental cellular process that can become harmful for cells by leading to DNA damage, for instance by an increase in oxidative stress or through the generation of toxic byproducts. To deal with such insults, cells have evolved sophisticated DNA damage response (DDR) pathways that...

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Detalles Bibliográficos
Autores principales: Moretton, Amandine, Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463900/
https://www.ncbi.nlm.nih.gov/pubmed/32722390
http://dx.doi.org/10.3390/cancers12082051