Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation

The aim of this study was to control the dissolution rate and permeability of cilostazol. To enhance the dissolution rate of the active pharmaceutical ingredient (API), hot-melt extrusion (HME) technology was applied to prepare a solid dispersion (SD). To control permeability in the gastrointestinal...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Sung-Min, Lee, Sung-Hoon, Kang, Chin-Yang, Park, Jun-Bom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463902/
https://www.ncbi.nlm.nih.gov/pubmed/32796665
http://dx.doi.org/10.3390/pharmaceutics12080757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463902/
https://www.ncbi.nlm.nih.gov/pubmed/32796665
http://dx.doi.org/10.3390/pharmaceutics12080757

Ejemplares similares