Neuroprotective Effect of HIF Prolyl Hydroxylase Inhibition in an In Vitro Hypoxia Model

A novel potent analog of the branched tail oxyquinoline group of hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors, neuradapt, has been studied in two treatment regimes in an in vitro hypoxia model on murine primary hippocampal cultures. Neuradapt activates the expression of HIF1 and HIF2...

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Detalles Bibliográficos
Autores principales: Savyuk, Maria, Krivonosov, Mikhail, Mishchenko, Tatiana, Gazaryan, Irina, Ivanchenko, Mikhail, Khristichenko, Anna, Poloznikov, Andrey, Hushpulian, Dmitry, Nikulin, Sergey, Tonevitsky, Evgeny, Abuzarova, Guzal, Mitroshina, Elena, Vedunova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463909/
https://www.ncbi.nlm.nih.gov/pubmed/32722310
http://dx.doi.org/10.3390/antiox9080662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463909/
https://www.ncbi.nlm.nih.gov/pubmed/32722310
http://dx.doi.org/10.3390/antiox9080662

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