The Interaction of Fluorinated Glycomimetics with DC-SIGN: Multiple Binding Modes Disentangled by the Combination of NMR Methods and MD Simulations

Fluorinated glycomimetics are frequently employed to study and eventually modulate protein–glycan interactions. However, complex glycans and their glycomimetics may display multiple binding epitopes that enormously complicate the access to a complete picture of the protein–ligand complexes. We herei...

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Detalles Bibliográficos
Autores principales: Martínez, J. Daniel, Infantino, Angela S., Valverde, Pablo, Diercks, Tammo, Delgado, Sandra, Reichardt, Niels-Christian, Ardá, Ana, Cañada, Francisco Javier, Oscarson, Stefan, Jiménez-Barbero, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463913/
https://www.ncbi.nlm.nih.gov/pubmed/32759765
http://dx.doi.org/10.3390/ph13080179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463913/
https://www.ncbi.nlm.nih.gov/pubmed/32759765
http://dx.doi.org/10.3390/ph13080179

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