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Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome

One of the most conserved cellular pathways among eukaryotes is the extensively studied classical protein nuclear import pathway mediated by importin-α. Classical nuclear localization signals (cNLSs) are recognized by importin-α and are highly predictable due to their abundance of basic amino acids....

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Detalles Bibliográficos
Autores principales: Tessier, Tanner M., MacNeil, Katelyn M., Mymryk, Joe S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463951/
https://www.ncbi.nlm.nih.gov/pubmed/32718019
http://dx.doi.org/10.3390/biology9080188