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Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction
The clinical successes of chimeric antigen receptor (CAR)-T-cell therapy targeting cell surface antigens in B cell leukaemias and lymphomas has demonstrated the proof of concept that appropriately engineered T-cells have the capacity to destroy advanced cancer with long term remissions ensuing. Neve...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463974/ https://www.ncbi.nlm.nih.gov/pubmed/32824734 http://dx.doi.org/10.3390/cancers12082326 |