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Metastasis of Uveal Melanoma with Monosomy-3 Is Associated with a Less Glycogenetic Gene Expression Profile and the Dysregulation of Glycogen Storage

The prolonged storage of glucose as glycogen can promote the quiescence of tumor cells, whereas the accumulation of an aberrant form of glycogen without the primer protein glycogenin can induce the metabolic switch towards a glycolytic phenotype. Here, we analyzed the expression of n = 67 genes invo...

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Detalles Bibliográficos
Autores principales: Vardanyan, Siranush, Brosig, Anton, Merz, Hartmut, Ranjbar, Mahdy, Kakkassery, Vinodh, Grisanti, Salvatore, Tura, Aysegül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463985/
https://www.ncbi.nlm.nih.gov/pubmed/32751097
http://dx.doi.org/10.3390/cancers12082101