Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches

Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are the two crucial enzymes involved in the pathology of Alzheimer’s disease. The former is responsible for many defects in cholinergic signaling pathway and the latter is the primary enzyme in the biosynthesis of beta-amyloid as the main compo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Thai-Son, Le, Minh-Tri, Tran, Thanh-Dao, Tran, The-Huan, Thai, Khac-Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464027/
https://www.ncbi.nlm.nih.gov/pubmed/32785161
http://dx.doi.org/10.3390/molecules25163644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464027/
https://www.ncbi.nlm.nih.gov/pubmed/32785161
http://dx.doi.org/10.3390/molecules25163644

Ejemplares similares