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Genomic, microbial and environmental standardization in animal experimentation limiting immunological discovery

BACKGROUND: The use of inbred mice housed under standardized environmental conditions has been critical in identifying immuno-pathological mechanisms in different infectious and inflammatory diseases as well as revealing new therapeutic targets for clinical trials. Unfortunately, only a small percen...

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Detalles Bibliográficos
Autores principales: Enriquez, Josue, Mims, Brianyell Mc Daniel, Trasti, Scott, Furr, Kathryn L., Grisham, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464063/
https://www.ncbi.nlm.nih.gov/pubmed/32878597
http://dx.doi.org/10.1186/s12865-020-00380-x