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Adenosine Receptor Agonists Increase the Inhibition of Platelet Function by P2Y(12) Antagonists in a cAMP- and Calcium-Dependent Manner

We have shown previously that platelet activity can be lowered through the simultaneous inhibition of P2Y(12) receptor and activation of adenosine receptors (AR). This work explores this concept by testing the antiplatelet potential of nine AR agonists in combination with P2Y(12) receptor antagonist...

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Detalles Bibliográficos
Autores principales: Wolska, Nina, Kassassir, Hassan, Luzak, Boguslawa, Watala, Cezary, Rozalski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464091/
https://www.ncbi.nlm.nih.gov/pubmed/32752089
http://dx.doi.org/10.3390/ph13080177