Conformational Equilibrium of NADPH–Cytochrome P450 Oxidoreductase Is Essential for Heme Oxygenase Reaction

Heme oxygenase (HO) catalyzes heme degradation using electrons supplied by NADPH–cytochrome P450 oxidoreductase (CPR). Electrons from NADPH flow first to FAD, then to FMN, and finally to the heme in the redox partner. Previous biophysical analyses suggest the presence of a dynamic equilibrium betwee...

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Detalles Bibliográficos
Autores principales: Sugishima, Masakazu, Taira, Junichi, Sagara, Tatsuya, Nakao, Ryota, Sato, Hideaki, Noguchi, Masato, Fukuyama, Keiichi, Yamamoto, Ken, Yasunaga, Takuo, Sakamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464098/
https://www.ncbi.nlm.nih.gov/pubmed/32731542
http://dx.doi.org/10.3390/antiox9080673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464098/
https://www.ncbi.nlm.nih.gov/pubmed/32731542
http://dx.doi.org/10.3390/antiox9080673

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