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Rapid Ex-Vivo Ciliogenesis and Dose-Dependent Effect of Notch Inhibition on Ciliogenesis of Respiratory Epithelia

Background: Cilia are actin based cellular protrusions conserved from algae to complex multicellular organisms like Homo sapiens. Respiratory motile cilia line epithelial cells of the tracheobronchial tree, beat in a synchronous, metachronal wave, moving inhaled pollutants and pathogens cephalad. Th...

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Detalles Bibliográficos
Autores principales: Zahid, Maliha, Feinstein, Timothy N., Oro, Anthony, Schwartz, Molly, Lee, Alex D., Lo, Cecilia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464104/
https://www.ncbi.nlm.nih.gov/pubmed/32823934
http://dx.doi.org/10.3390/biom10081182