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Rapid Ex-Vivo Ciliogenesis and Dose-Dependent Effect of Notch Inhibition on Ciliogenesis of Respiratory Epithelia
Background: Cilia are actin based cellular protrusions conserved from algae to complex multicellular organisms like Homo sapiens. Respiratory motile cilia line epithelial cells of the tracheobronchial tree, beat in a synchronous, metachronal wave, moving inhaled pollutants and pathogens cephalad. Th...
Autores principales: | Zahid, Maliha, Feinstein, Timothy N., Oro, Anthony, Schwartz, Molly, Lee, Alex D., Lo, Cecilia W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464104/ https://www.ncbi.nlm.nih.gov/pubmed/32823934 http://dx.doi.org/10.3390/biom10081182 |
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