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Genetic and Epigenetic Regulation of the Smoothened Gene (SMO) in Cancer Cells

(1) Background: The hedgehog (HH) signaling pathway is a key regulator of embryonic patterning, tissue regeneration, stem cell renewal, and cancer growth. The smoothened (SMO) protein regulates the HH signaling pathway and has demonstrated oncogenic activity. (2) Methods: To clarify the role of the...

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Detalles Bibliográficos
Autores principales: Lou, Hong, Li, Hongchuan, Huehn, Andrew R., Tarasova, Nadya I., Saleh, Bahara, Anderson, Stephen K., Dean, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464114/
https://www.ncbi.nlm.nih.gov/pubmed/32784501
http://dx.doi.org/10.3390/cancers12082219