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Imaging of Fibroblast Activation Protein Alpha Expression in a Preclinical Mouse Model of Glioma Using Positron Emission Tomography

Glioblastoma multiforme (GBM) is the most aggressive glioma of the primary central nervous system. Due to the lack of effective treatment options, the prognosis for patients remains bleak. Fibroblast activation protein alpha (FAP), a 170 kDa type II transmembrane serine protease was observed to be e...

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Detalles Bibliográficos
Autores principales: Pandya, Darpan N., Sinha, Akesh, Yuan, Hong, Mutkus, Lysette, Stumpf, Kristina, Marini, Frank C., Wadas, Thaddeus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464128/
https://www.ncbi.nlm.nih.gov/pubmed/32806623
http://dx.doi.org/10.3390/molecules25163672