Exogenous Flupirtine as Potential Treatment for CLN3 Disease

CLN3 disease is a fatal neurodegenerative disorder affecting children. Hallmarks include brain atrophy, accelerated neuronal apoptosis, and ceramide elevation. Treatment regimens are supportive, highlighting the importance of novel, disease-modifying drugs. Flupirtine and its new allyl carbamate der...

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Detalles Bibliográficos
Autores principales: Maalouf, Katia, Makoukji, Joelle, Saab, Sara, Makhoul, Nadine J., Carmona, Angelica V., Kinarivala, Nihar, Ghanem, Noël, Trippier, Paul C., Boustany, Rose-Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464162/
https://www.ncbi.nlm.nih.gov/pubmed/32796515
http://dx.doi.org/10.3390/cells9081872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464162/
https://www.ncbi.nlm.nih.gov/pubmed/32796515
http://dx.doi.org/10.3390/cells9081872

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