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Finding a Jill for JAK: Assessing Past, Present, and Future JAK Inhibitor Combination Approaches in Myelofibrosis

Myelofibrosis (MF) is a myeloproliferative neoplasm hallmarked by the upregulation of the Janus kinase (JAK)—signal transducer and activator of transcription (STAT) pathway with associated extramedullary hematopoiesis and a high burden of disease-related symptoms. While JAK inhibitor therapy is cent...

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Detalles Bibliográficos
Autores principales: Kuykendall, Andrew T., Horvat, Nathan P., Pandey, Garima, Komrokji, Rami, Reuther, Gary W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464183/
https://www.ncbi.nlm.nih.gov/pubmed/32823910
http://dx.doi.org/10.3390/cancers12082278