Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death

Background: The epidermal growth factor receptor (EGFR) signaling pathway is genetically activated in approximately 50% of glioblastomas (GBs). Its inhibition has been explored clinically but produced disappointing results, potentially due to metabolic effects that protect GB cells against nutrient...

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Detalles Bibliográficos
Autores principales: Luger, Anna-Luisa, Lorenz, Nadja I., Urban, Hans, Divé, Iris, Engel, Anna L., Strassheimer, Florian, Dettmer, Katja, Zeiner, Pia S., Shaid, Shabnam, Struve, Nina, Kriegs, Malte, Hofmann, Ute, Oefner, Peter J., Harter, Patrick N., Steinbach, Joachim P., Ronellenfitsch, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464192/
https://www.ncbi.nlm.nih.gov/pubmed/32756332
http://dx.doi.org/10.3390/cancers12082144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464192/
https://www.ncbi.nlm.nih.gov/pubmed/32756332
http://dx.doi.org/10.3390/cancers12082144

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