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Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death
Background: The epidermal growth factor receptor (EGFR) signaling pathway is genetically activated in approximately 50% of glioblastomas (GBs). Its inhibition has been explored clinically but produced disappointing results, potentially due to metabolic effects that protect GB cells against nutrient...
Autores principales: | Luger, Anna-Luisa, Lorenz, Nadja I., Urban, Hans, Divé, Iris, Engel, Anna L., Strassheimer, Florian, Dettmer, Katja, Zeiner, Pia S., Shaid, Shabnam, Struve, Nina, Kriegs, Malte, Hofmann, Ute, Oefner, Peter J., Harter, Patrick N., Steinbach, Joachim P., Ronellenfitsch, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464192/ https://www.ncbi.nlm.nih.gov/pubmed/32756332 http://dx.doi.org/10.3390/cancers12082144 |
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