Effect of Cladribine on Neuronal Apoptosis: New Insight of In Vitro Study in Multiple Sclerosis Therapy

Background: Cladribine (2-CdA) can cross the blood–brain barrier, resulting in inhibition of DNA synthesis and repair and disruption of cellular proliferation in actively dividing lymphocytes. No data on effect on neurons are available. Aim: To study “in vitro” 2-CdA apoptotic effects on neurons in...

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Detalles Bibliográficos
Autores principales: Ruggieri, Maddalena, Gargano, Concetta Domenica, Ferretta, Anna, Manni, Alessia, Capacchione, Antonio, Frigeri, Antonio, Iaffaldano, Pietro, Trojano, Maria, Paolicelli, Damiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464206/
https://www.ncbi.nlm.nih.gov/pubmed/32823496
http://dx.doi.org/10.3390/brainsci10080548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464206/
https://www.ncbi.nlm.nih.gov/pubmed/32823496
http://dx.doi.org/10.3390/brainsci10080548

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