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Current Landscape of NRF2 Biomarkers in Clinical Trials

The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) plays a critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the regulation of inflammation and cellular detoxication pathways. The contribution of the NRF2 pathway to organismal homeost...

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Detalles Bibliográficos
Autores principales: Yagishita, Yoko, Gatbonton-Schwager, Tonibelle N., McCallum, Melissa L., Kensler, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464243/
https://www.ncbi.nlm.nih.gov/pubmed/32784785
http://dx.doi.org/10.3390/antiox9080716