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Pre-Existing Tumoral B Cell Infiltration and Impaired Genome Maintenance Correlate with Response to Chemoradiotherapy in Locally Advanced Rectal Cancer

Locally advanced rectal cancer (LARC) remains a medical challenge. Reliable biomarkers to predict which patients will significantly respond to neoadjuvant chemoradiotherapy (nCRT) have not been identified. We evaluated baseline genomic and transcriptomic features to detect differences that may help...

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Detalles Bibliográficos
Autores principales: Sendoya, Juan M., Iseas, Soledad, Coraglio, Mariana, Golubicki, Mariano, Robbio, Juan, Salanova, Ruben, Kujaruk, Mirta, Mikolaitis, Vanesa, Rizzolo, Mariana, Ruiz, Gonzalo, Cabanne, Ana, Gualdrini, Ubaldo, Mendez, Guillermo, Hirmas, Stella, Rotondaro, Cecilia, Viglino, Julieta, Eleta, Martín, Fernandez, Elmer, Abba, Martín, Podhajcer, Osvaldo, Roca, Enrique, Llera, Andrea S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464257/
https://www.ncbi.nlm.nih.gov/pubmed/32784964
http://dx.doi.org/10.3390/cancers12082227